Alzheimer’s Nutrigenomics

Alzheimer’s Nutrigenomics is an exciting new field that combines “nutrition” and “genetics” to address cognitive decline issues.  Scientists have discovered that our genes are in fact “switched on” or “off” by the foods we eat, exercise and lifestyle choices.

DNA testing is painless and simple (saliva collection not blood) and allows you to make informed decisions for truly personalised health care.

We offer a large range of DNA tests for general health along with specialist panels for common disease states including  Alzheimers, Osteoporosis, Cardiac, Macular Degeneration, Obesity/ Weight loss, Coeliac, Histamine and Vitamins, Thyroid, Anaesthesia and adverse drug reactions and Hemochromatosis.

We use science based targeted interventions and prevention strategies.

You will receive a comprehensive Bio-individualised report using the latest evidence based interventions based on your genes

The most important thing that you can do to control your genes every day is to eat “real food” not “junk food”.  The combination and quality of protein, fat, carbohydrates, vitamins, minerals, fibre, and phytonutrients all affect your DNA every day. They turn on or off, up or down signals from your genes. Nutrigenomics thus offers a powerful way to have more control over your destiny.

Researchers have found, for example, that depending on your genes, you may respond better to different diets – some do better with more fat and protein and less carbs, others may not. One of the most important discoveries of the decade is how food – whether it is plant-based, nutrient-rich, phytonutrients-rich food, or processed, high sugar, nutrient-depleted food – changes your gene expression in real time over the course of literally just a few months.

Lots of people take nutritional supplements to try and make up for what they lack in their diet. Many people don’t really know what the supplements do. They tend to have a “take it and see what happens” approach. For the most part, the body doesn’t get what it actually needs. Nutrigenomics takes the guess work out of it, and puts you in control.

We can take a simple saliva sample, which is sequenced, analysed and returned to us as a personalised genetic profile. We are able to take a holistic approach to reveal what foods or nutritional supplements will benefit you the most. This eliminates any guesswork as the treatment plan is based on your own genes.

We will carefully choose an appropriate gene panel for you. We address many areas affecting Alzheimer’s and cognitive decline such as:

• Inflammation / inflammatory markers and detoxification genes
• Better sleeping patterns – oxidative stress, methylation
• Regulation of hormone imbalances – methylation genes
• Cholesterol regulation genes, cell defense genes
• Mental Health – methylation genes
• Weight loss /gain – fat metabolism, insulin and thermogenesis genes
• Energy and vitality – anti-oxidant status genes
• Vitamin receptor genes

These genes have a major impact on a person’s overall health.

How can I organise a testing?

If you would like to join our program including personalised genetic profiling, please contact us today to book your consultation. Ph +617 3878 4704 or click the contact us button below.

References:

Guide and position of the international society of nutrigenetics/nutrigenomics on personalised nutrition: part 1 – fields of precision nutrition. Ferguson L. R., De Caterina R., Görman U., Allayee H., Kohlmeier M., Prasad C., et al. (2016). J. Nutrigenet. Nutrigenomics. 9, 12–27.

Hindawi Publishing Corporation, Oxidative and cellular longevity volume 2016, Article ID 7857186. 17 pages 6th Dec 2016 Sulforaphane and other Nutrigenomic Nrf2 activators: Can the clinician’s expectation be matched by the reality? Houghton C, Fassett R, Coombes J.

Effect of Sulforaphane on NOD2 via NF-κB: implications for Crohn’s disease. Danielle L Folkard, Gareth Marlow, Richard F Mithen, Lynnette R Ferguson J Inflamm (Lond) 2015; 12: 6.

Protective effect of sulforaphane against oxidative stress: recent advances. Guerrero-Beltran CE, Caldersn-Oliver M, Pedraza-Chaverri J, Chirino YI., Exp Toxicol Pathol. 2012 Jul;64(5):503-8.

Omega-3 fatty acids and inflammatory processes. Calder PC,  Nutrients. 2012 Mar;2(3):355-74.

Vitamins D,C and E in the prevention of type 2 diabetes mellitus: modulation of inflammation and oxidative stress. Garcia-Bailo, B., El-Sohemy, A., Haddad, P., et al. Biologics. 2011. 5. 7-19.

Stress, Food, and Inflammation: Psychoneuroimmunology and Nutrition at the Cutting Edge. Kiecolt-Glaser, JK. Psychosomatic Medicine May 2010 vol. 72 no. 4, 365-369.

Influence of IL-6, COL1A1, and VDR gene polymorphisms on bone mineral density in Crohns disease. Todhunter, C., Sutherland-Craggs, A., Bartram, S. Gut. 2005. 54, 1579-1584

CYP1A2, GSTM1 and GSTT1 polymorphisms and diet effects on CYP1A2 activity in a crossover feeding trial. Peterson, S., Schwartz, Y., Li, S.  Cancer Epidemiol Biomarkers and Prevention. 2009. 18; 3118

Inhibition of human catechol-o-methyltransferase (COMT)-mediated O-methylation of catechol estrogens by major polyphenolic components present in coffee. Zhu, B., Wang, P., Nagai, M., et al. J Steroid Biochem Mol Biol. 2009. 113(1-2); 65-74

Genetic basis for individual variations in pain perception and the development of a chronic pain condition. Diatchenko, L., Slade, G., Nackley, A., et al. Hum Mol Genet. 2005.14(1) 135-143.

Vitamin D receptor activity and prevention of colonic hyperproliferation and oxidative stress. Kallay, E., Bajna, E., Kriwanek, S, et al. Food and Chemical Toxicity. 2002. Vol 40, Issue 8. 1191-1196.

The effect on human tumor necrosis factor alpha and interleukin 1 beta production of diets enriched in n-3 fatty acids from vegetable oil or fish oil. Caughey, GE, Mantzioris, E., Gibson, RA, et al Am J Clin Nutr January 1996 vol. 63 no. 1 116-122

Nutrigenomics article pdf,www.cell-logic.com.au June 2013. Nutrigenomics – taking nutritional medicine to the next level Houghton C.

www.cell-logic.com.au/wp-content/uploads/Whats_the difference_Nutrigenomics_Epigenetics2013.pdf  Nutrigenomics? Epigenetics? The must-know buzzwords of 21st century health care Houghton C.